The problem isn't what we don't know - it's what we think we know. That mass of information and experience you tend to take as 'you'. All of which simply does not add up! You want to be free of it. But, within that confusion is all the material that you 'think' from, and have your sense of 'I' within. Without that ignorance - 'you' do not exist.
That ignorance is the giant issue. It's who you think you are.
......................
It's nonsense, it's illusion, all within the darkness.
If you put the light of observation on all of that it has the effect of dissolving the pictures that were held together with, as I sometimes say, 'scotch tape and spit'. Even a little light starts to melt it. Separate, look back at it - and get a smile on your face.